There is a significant need for rapid, quantitative, single-molecule sensitive profiling technologies that do not require up-front assumptions about what will be found in a sample. For example, a patient with a bacterial bloodstream infection could harbor any number of common pathogens, and their chances of survival go down with every hour that they remain incorrectly diagnosed. The Fraley Lab has the aim of democratizing data generation on a patient level, making technologies that are accessible, affordable, and easy to use. By applying microfluidic, optical, engineering, and computational approaches, we develop technology that requires fewer assumptions while providing quantitative, sensitive, and specific details at the single cell level. 

From the benchtop...

To the bedside...